77 research outputs found

    Becoming a psychologist : tracing life histories in South Africa

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    Bibliography: leaves 153-161.This study explores and aims to identify the narratives found amongst professional psychologists and the establishment of a professional identity in the process of becoming and being a psychologist. It is interested in this process of becoming a psychologist specifically within the South African social context, which may influence the professional development and identity of local psychologists

    Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis

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    Abstract Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) seem to be opposite entities from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases. Emphysema is caused by an elastase/anti-elastase imbalance leading to accelerated elastin degradation. Elastinolysis is however, also accelerated in the IPF patients’ lungs. The amino acids desmosine and isodesmosine (DES) are unique to elastin. During the degradation process, elastases liberate DES from elastin fibers. Blood DES levels consequently reflect the rate of systemic elastinolysis and are increased in COPD. This is the first report describing elevated DES levels in IPF patients. We also demonstrated that the age-related increment of DES concentrations is enhanced in IPF. Our current study suggests that elastinolysis is a shared pathogenic step in both COPD and IPF. Further investigation is required to establish the relevance of accelerated elastin degradation in IPF and to determine whether decelerating this process leads to slower progression of lung fibrosis and better survival for patients with IPF.https://deepblue.lib.umich.edu/bitstream/2027.42/142803/1/12931_2018_Article_747.pd

    Understanding the burden of injuries in Nepal: A systematic review of published studies

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    BackgroundThe population of Nepal are vulnerable to injuries from natural disasters as well as those occurring in the home, at work and on the roads.AimTo collate and synthesise the published literature reporting injuries to people of any age resident in Nepal.MethodWe searched five electronic databases using an inclusive search strategy. Potentially eligible citations were screened by title and abstract and full texts of studies obtained. Data were extracted by two researchers. Synthesis was reported narratively by injury type and study design.ResultsWe identified 186 publications reporting 176 unique studies. Most studies used designs likely to underestimate the true burden of disease, including 144 case series and 36 cross-sectional studies. No trials were identified. The largest number of publications were related to poisoning and self-harm with only 22 focussing on road traffic injuries. There was minimal exploration of inequalities in injury occurrence other than descriptive reporting by age and gender. ConclusionsThere is limited research using study designs at low risk of bias on injuries occurring to residents of Nepal, even on areas of concern such as road traffic injuries. The findings indicate a lack of robust epidemiological evidence to inform strategic approaches to injury prevention and suggest a need for capacity strengthening for injury prevention research

    Exploring synergies and trade-offs among the sustainable development goals: collective action and adaptive capacity in marginal mountainous areas of India

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    Global environmental change (GEC) threatens to undermine the sustainable development goals (SDGs). Smallholders in marginal mountainous areas (MMA) are particularly vulnerable due to precarious livelihoods in challenging environments. Acting collectively can enable and constrain the ability of smallholders to adapt to GEC. The objectives of this paper are: (i) identify collective actions in four MMA of the central Indian Himalaya Region, each with differing institutional contexts; (ii) assess the adaptive capacity of each village by measuring livelihood capital assets, diversity, and sustainable land management practices. Engaging with adaptive capacity and collective action literatures, we identify three broad approaches to adaptive capacity relating to the SDGs: natural hazard mitigation (SDG 13), social vulnerability (SDG 1, 2 and 5), and social–ecological resilience (SDG 15). We then develop a conceptual framework to understand the institutional context and identify SDG synergies and trade-offs. Adopting a mixed method approach, we analyse the relationships between collective action and the adaptive capacity of each village, the sites where apparent trade-offs and synergies among SDGs occur. Results illustrate each village has unique socio-environmental characteristics, implying distinct development challenges, vulnerabilities and adaptive capacities exist. Subsequently, specific SDG synergies and trade-offs occur even within MMA, and it is therefore crucial that institutions facilitate locally appropriate collective actions in order to achieve the SDGs. We suggest that co-production in the identification, prioritisation and potential solutions to the distinct challenges facing MMA can increase understandings of the specific dynamics and feedbacks necessary to achieve the SDGs in the context of GEC

    Desastres naturais: convivĂȘncia com o risco

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    Estudos sobre riscos de desastres naturais tĂȘm-se aprimorado de uma abordagem fisicalista para uma perspectiva socioambiental. No entanto, planejamento e gestĂŁo ainda seguem o paradigma antropocĂȘntrico da superioridade humana e do poder ilimitado da ciĂȘncia e tecnologia. Evidencia-se uma incapacidade cognitiva, cultural e de ação por parte de especialistas, cientĂ­ficos e tomadores de decisĂŁo (claimmakers) para identificar e atuar sobre as causas sociais da produção de risco. Frente a uma ciĂȘncia cartesiana e positivista na resolução de problemas, baseada na segurança e controle sobre o mundo natural, propĂ”e-se uma ciĂȘncia pĂłs-normal que considera os riscos e incertezas do conhecimento cientĂ­fico e das problemĂĄticas ambientais. Essa nova proposta tambĂ©m incide sobre a participação e o diĂĄlogo entre stakeholders como referĂȘncia para ampliar a qualidade do saber cientĂ­fico e o entendimento da complexidade das questĂ”es ambientais. Este artigo discute a necessidade de se promover um salto epistemolĂłgico sobre a forma de pensar e produzir conhecimentos, bem como implementar a gestĂŁo dos riscos de desastres, tendo como objeto de estudo processos de comunicação e educação para prevenção de desastres.Studies on the risks of natural disasters have improved from a physicalist approach to a social and environmental perspective. However, planning and management still follow the anthropocentric paradigm of human superiority and the unlimited power of science and technology, evincing a cognitive, cultural and action inability on the part of experts, scientists and decision makers (or, rather, claim makers) to identify and act upon the social causes of risk production. In view of the Cartesian and Positivist science used to solve problems, based on security and on control over the natural world, a post-normal science has been proposed that considers the risks and uncertainties of scientific knowledge and environmental issues. This new approach encompasses participation and dialogue among stakeholders as a means to increase the quality of scientific knowledge and acknowledge the complexity of environmental issues. This article discusses the need for an epistemological leap on how we think and produce knowledge, as well as for implementing the management of disaster risk. Its objects of study are communication processes and education for disaster prevention

    Global Platform for Disaster Risk Reduction: supporting international frameworks through science and technology

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    The recent United Nations (UN) Global Platform for Disaster Risk Reduction (DRR), held in Cancun, Mexico from 22-26 May 2017, is the fifth version of a biennial meeting of researchers, practitioners and policymakers. Starting in 2007, the meetings reflect UN-level efforts to reduce escalating hazards and disaster risks worldwide

    Global Platform for Disaster Risk Reduction: supporting international frameworks through science and technology

    No full text
    The recent United Nations (UN) Global Platform for Disaster Risk Reduction (DRR), held in Cancun, Mexico from 22-26 May 2017, is the fifth version of a biennial meeting of researchers, practitioners and policymakers. Starting in 2007, the meetings reflect UN-level efforts to reduce escalating hazards and disaster risks worldwide
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